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New rabies virus identified
African civets are nocturnal, cat-like animals. A case of a child being bitten by a rabid civet has led researchers to a new species of virus that causes rabies. The new species is sufficiently...
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Wellcome Image of the Month: TB Warning
March 24th is World Tuberculosis Day. It commemorates the day in 1882 when Dr Robert Koch announced he had discovered the cause of TB by successfully isolating the bacteria Mycobacterium tuberculosis,...
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A new global strategy for TB vaccines
An X-ray showing pulmonary tuberculosis in the left lung (right of picture) Tomorrow, Saturday 24 March, it will be exactly 130 years since Robert Koch identified the cause of tuberculosis (TB) and...
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40 years of tropical epidemiology
General population survey undertaken by the MRC unit in Uganda An international symposium on epidemiology and global health also celebrates 40 years of a group dedicated to providing epidemiological...
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Sustain gains, save lives: invest in malaria
Malaria - artwork - mosquitos and text Malaria has always fascinated me. One of the oldest diseases known to mankind, it has played an important role in historical turning points, from the fall of the...
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The impact of 20 years of malaria research
Landmarks in malaria timeline. Click to open or download the full PDF. To coincide with World Malaria Day, we’re publishing of the Wellcome Trust Malaria Portfolio Review. Claire Vaughan summarises its...
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Wellcome Film of the Month: The Wellcome Trust in Thailand (1987)
This week we launched a 20 year review of research into malaria, coinciding with World Malaria Day. This film portrays the work of the Wellcome Trust-supported clinical research unit based in Mahidol...
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Wellcome Film of the Month: Defeat tuberculosis (1950)
This month’s film was produced by the government funded Central Office of Information for the Ministry of Health. The Central Office of Information was established in 1946 as the successor to the...
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Q&A: Vicky Robinson – answering a difficult question with the 3Rs
A researcher handling a mouse. The use of animals in research is one of the most difficult and emotive ethical dilemmas confronting the life sciences. Few of us are comfortable with the thought, but,...
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From bench to field: Most advanced TB vaccine in pivotal trials
An eager trial participant in the MVA85A phase IIB infant trial in South Africa. Professor Helen McShane writes from the frontline of efforts to develop the first new TB vaccine in 90 years. The...
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Wellcome Image of the Month: World Rabies Day
What deadly disease results in symptoms including fever, hydrophobia, hallucinations and paralysis? Rabies, of course. A viral infection targeting the brain and nervous system, rabies affects over...
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TB: When the drugs don’t work
An X-ray showing pulmonary tuberculosis in the left lung (right of picture) Kathryn Lougheed on why tuberculosis is still a problem and the key role of basic research in tackling it. When I tell people...
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Sticking points in HIV treatment
‘“Why did you stop taking the drugs?” ‘I tell them, “I have stopped because I don’t have enough food.” Then they say, “You must not stop! […] Eat and take your medicine!” ‘Their thoughts and my...
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Family planning for mosquitoes: Genetically modified insects to fight dengue...
Aedes aegypti mosquito We’re publishing the shortlisted entries to the 2012 Wellcome Trust Science Writing Prize. Here, Michael Conway writes about efforts to stop the spread of dengue fever by using...
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The strange future of antibiotics
We’re publishing the shortlisted entries to the 2012 Wellcome Trust Science Writing Prize. Here, Russell Fraser on the paucity of new antibiotics and the unusual new armaments in the war against...
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How can history help the global health community today?
False coloured light micrograph of MRSA colonies. Methicillin-resistant Staphylococcus aureus (MRSA) is a bacterium which is difficult to treat due to its resistance to common forms of antibiotics. The...
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The Livingstone Legacy
David Livingstone and his followers on a boat, attacked by a hippopotamus. From abolishing slavery in Africa to changing the face of tropical medicine, David Livingstone was an extraordinary man. Mike...
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NTDs: The London Declaration, one year on
This time last year, a group of politicians, charities and pharmaceutical companies came to London to sign a pledge. They committed to either bring under control or eliminate ten diseases by 2020; ten...
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HAT tip: researchers map African sleeping sickness
Above: One of the maps produced by the study. The map shows the distribution of HAT risk in Congo, with five deepening shades of colour representing five categories of risk from ‘very low’ to ‘very...
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Feature: The biggest poisoning in history
One of the more bitter ironies of human existence is the way the best of our intentions can fall foul of Murphy’s Law and wind up as paving stones on the proverbial road to hell. A recent, devastating...
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